2B3_0728_ ELECTROSPUN KERATIN/POLY(BUTYLENE SUCCINATE) MATS FOR WOUND HEALING AND DRUG DELIVERY APPLICATIONS

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Annalisa Aluigi

T. Posati

G. Sotgiu

R. Zamboni

G. Guidotti

M. Soccio

A. Munari

N. Lotti

M. Barbalinardo

F. Valle

Published Aug 13, 2019

Abstract

Regenerated wool keratin is a promising natural material for wound dressing. In the present study, keratin extracted from wool was blended with poly(butylene succinate) in 1,1,1,3,3,3-hexafluoro-2-propanol (blending ratio 50/50) and electrospun into nanofibrous mats. Compared to the pure poly(butylene succinate) nanofibres, the keratin based ones showed lower diameters, lower mechanical properties but an increased biodegradability, a delayed diclofenac release and increased bioactivity.


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