The microorganism Cupriavidus necator has been chosen as a platform to biologically transform CO2 from gas streams into 3-hydroxypropionic acid (3-HP) inside trickle bed reactors. Usually, packing materials are used as a support for microorganisms’ adhesion and growth. To optimize the production of 3-HP this study aims to develop advanced packing materials with improved surface and sorption properties. Hardwood, polyurethane and polyisocyanurate-based foams, polypropylene pellets and polyester textiles have been studied as innovative packing materials, and compared with Raschig rings, as standard packing materials. An evaluation of contact angle, surface morphology, surface area, porosity and biofilm formation has been performed.